SCHEMBL2409172

SCHEMBL2409172

C/S(=N\C#N)C1CCC(c2ccc(Cl)nc2)C1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 9/20 0.36
CHRNA4 P43681 7/20 0.36
CHRNA7 P36544 6/20 0.36
CHRNA3 P32297 5/20 0.36
CHRNB4 P30926 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CHRNA1 P02708 1/20 0.35
CHRNG P07510 1/20 0.35
CHRNB1 P11230 1/20 0.35
HPGD P15428 1/20 0.35
CHRND Q07001 1/20 0.35
CHRNA2 Q15822 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2409175 1.00 CHRNB2 (0.36) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL18929480 0.76 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL4038673 0.76 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL1959230 0.76 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL6979310 0.76 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL1959231 0.76 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL30847846 0.72 CHRNB2 (0.53) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL1481609 0.72 CHRNB2 (0.53) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
Cyanide SCHEMBL27676360 0.70 CHRNB2 (0.49) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4
SCHEMBL2409548 0.70 CHRNB2 (0.35) CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183268-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES, LLC. (US) 2012-05-22 US disclosed
US-8183268-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES, LLC. (US) 2012-05-22 US disclosed
US-8183268-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES, LLC. (US) 2012-05-22 US disclosed
US-8017788-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2011-09-13 US disclosed
US-8017788-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2011-09-13 US disclosed
US-8017788-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2011-09-13 US disclosed
US-20100173962-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES DOW AGROSCIENCES LLC (US) 2010-07-08 US disclosed
US-20100173962-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES DOW AGROSCIENCES LLC (US) 2010-07-08 US disclosed
US-20100173950-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES CORTEVA AGRISCIENCE LLC 2010-07-08 US disclosed
US-20100173950-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES CORTEVA AGRISCIENCE LLC 2010-07-08 US disclosed
US-20100168172-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES CORTEVA AGRISCIENCE LLC 2010-07-01 US disclosed
US-20100168172-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES CORTEVA AGRISCIENCE LLC 2010-07-01 US disclosed
US-20100168172-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES CORTEVA AGRISCIENCE LLC 2010-07-01 US disclosed
US-7705156-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2010-04-27 US disclosed
US-7705156-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2010-04-27 US disclosed
US-7705156-B2 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides DOW AGROSCIENCES LLC (US) 2010-04-27 US disclosed
WO-2008057131-A1 HETEROARYL (SUBSTITUTED) ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES DOW AGROSCIENCES LLC (US) 2008-05-15 WO disclosed
US-20080108666-A1 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides CORTEVA AGRISCIENCE LLC 2008-05-08 US disclosed
US-20080108666-A1 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides CORTEVA AGRISCIENCE LLC 2008-05-08 US disclosed
US-20080108666-A1 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides CORTEVA AGRISCIENCE LLC 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080108666-A1 Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides STS, DDT, TST CHRNB2 978/4885CHRNA4 1252/4885CHRNA7 1863/4885
US-20100173962-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES STS, DDT, TST CHRNB2 978/4885CHRNA4 1252/4885CHRNA7 1863/4885
US-20100173950-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES STS, DDT, TST CHRNB2 978/4885CHRNA4 1252/4885CHRNA7 1863/4885
US-20100168172-A1 HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES STS, DDT, TST CHRNB2 978/4885CHRNA4 1252/4885CHRNA7 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.