⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31415543 | 0.97 | CYP3A4 (0.56) | — | |
| SCHEMBL9602 | 0.79 | — | — | |
| SCHEMBL29418051 | 0.79 | — | — | |
| SCHEMBL17356182 | 0.79 | — | — | |
| SCHEMBL28455452 | 0.78 | KCNQ3 (0.38) | — | |
| Iodide SCHEMBL31415635 | 0.77 | CYP3A4 (0.56) | — | |
| Hydrochloric Acid SCHEMBL6186117 | 0.77 | CYP3A4 (0.56) | — | |
| Fluoride SCHEMBL27766501 | 0.77 | CYP3A4 (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL27721437 | 0.77 | CYP3A4 (0.56) | — | |
| SCHEMBL21835261 | 0.77 | MAOA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-114560811-B | 1,3, 5-trisubstituted-pyrazole-4 carboxylic acid derivative, preparation method and application thereof | 上海立森印迹医药技术有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-112409281-B | (E) Synthesis method of (E) -3- (3-chloro-2-fluoro-6- (1H-tetrazole-1-yl) phenyl) acrylic acid | 上海大学 | 2022-11-18 | — | — | CN | claimed |
| CN-114560811-A | 1,3, 5-trisubstituted-pyrazole-4 carboxylic acid derivative and preparation method and application thereof | 中国药科大学 | 2022-05-31 | — | — | CN | claimed |
| CN-109824583-B | Phenyl oxamide HIV-1 inhibitor and preparation method and application thereof | 山东大学 | 2022-04-08 | — | — | CN | claimed |
| CN-112409281-A | (E) Synthesis method of (E) -3- (3-chloro-2-fluoro-6- (1H-tetrazole-1-yl) phenyl) acrylic acid | 上海大学 | 2021-02-26 | — | — | CN | claimed |
| CN-110642741-A | Functionalized benzamide derivatives as antiviral agents against HBV infection | 巴鲁克斯布隆伯格研究所 | 2020-01-03 | — | — | CN | claimed |
| CN-109824583-A | A kind of phenyl Oxamides HIV-1 inhibitor and its preparation method and application | 山东大学 | 2019-05-31 | — | — | CN | claimed |
| US-20150307443-A1 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | BARUCH S BLUMBERG INST (US) | 2015-10-29 | — | — | US | claimed |
| EP-2928459-A2 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | Baruch S. Blumberg Institute (US) | 2015-10-14 | — | — | EP | claimed |
| US-20120115902-A1 | 3H-Imidazo [4, 5-B] Pyridine- 6 -Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-10 | — | — | US | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| WO-2010034799-A1 | 3H-IMIDAZ0 [4, 5-B] PYRIDINE- 6 -CARBOXAMIDES AS ANTI -INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| JP-2007523865-A | — | — | 2007-08-23 | — | — | JP | claimed |
| US-7129235-B2 | Amides useful for treating pain | ABBOTT LABORATORIES (US) | 2006-10-31 | — | — | US | claimed |
| EP-1646621-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | Abbott Laboratories (US) | 2006-04-19 | — | — | EP | claimed |
| US-20050080095-A1 | administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I | ABBVIE INC. | 2005-04-14 | — | — | US | claimed |
| WO-2005007642-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2005-01-27 | — | — | WO | claimed |