Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411007 | 0.91 | HTR2C (0.38) | HTR2CSLC6A4HTR2ARIPK1SSTR4 | |
| SCHEMBL29865792 | 0.74 | POLB (0.44) | HTR2CSLC6A4HTR2ASSTR4CACNA1G | |
| SCHEMBL1830977 | 0.72 | SSTR4 (0.38) | HTR2CSLC6A4HTR2ARIPK1SSTR4 | |
| SCHEMBL20794554 | 0.71 | HTR2C (0.43) | HTR2CSLC6A4HTR2ASSTR4CACNA1G | |
| SCHEMBL8017533 | 0.71 | HTR2C (0.47) | HTR2CSLC6A4RIPK1CACNA1GCACNA1B | |
| SCHEMBL24716134 | 0.70 | MAOA (0.54) | KMT2A | |
| SCHEMBL30626630 | 0.70 | MAOA (0.54) | KMT2A | |
| SCHEMBL2414689 | 0.70 | RIPK1 (0.35) | HTR2CSLC6A4HTR2ARIPK1SSTR4 | |
| SCHEMBL1834426 | 0.69 | HTR2C (0.33) | HTR2CSLC6A4HTR2ARIPK1SSTR4 | |
| SCHEMBL3700738 | 0.69 | HTR2C (0.44) | HTR2CSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |