SCHEMBL240959

SCHEMBL240959

CCCOC(=O)CC(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.52
GAA P10253 2/20 0.52
SI P14410 2/20 0.52
MGAM2 Q2M2H8 2/20 0.52
TSHR P16473 4/20 0.43
FAAH O00519 2/20 0.42
NAAA Q02083 1/20 0.41
DGKA P23743 1/20 0.41
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
POLB P06746 1/20 0.38
POLA1 P09884 1/20 0.38
LMNA P02545 1/20 0.38
ESR1 P03372 1/20 0.36
CHRM1 P11229 1/20 0.36
SLC6A2 P23975 1/20 0.36
KDR P35968 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240282 0.92 MGAM (0.60) MGAMGAASIMGAM2TSHR
Butane SCHEMBL28237119 0.90 MGAM (0.57) MGAMGAASIMGAM2TSHR
SCHEMBL28914455 0.90 MGAM (0.57) MGAMGAASIMGAM2TSHR
SCHEMBL14375215 0.87 MGAM (0.52) MGAMGAASIMGAM2TSHR
SCHEMBL1206456 0.86 ALDH1A1 (0.54) MGAMGAASIMGAM2TSHR
SCHEMBL240898 0.85 GAA (0.75) MGAMGAASIMGAM2FAAH
Malonic Acid Diethyl Ester SCHEMBL28059368 0.85 GAA (0.75) MGAMGAASIMGAM2FAAH
SCHEMBL18320875 0.84 NAAA (0.63) TSHRFAAHNAAADGKAALDH1A1
SCHEMBL28146594 0.83 GAA (0.58) MGAMGAASIMGAM2TSHR
SCHEMBL5268975 0.83 ALDH1A1 (0.56) MGAMGAASIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12359017-B2 Method for producing a rigid polyurethane foam BASF SE (DE) 2025-07-15 US claimed
CN-118290285-A Method for synthesizing amide 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-116730832-B Preparation method of 2-propyl caproic acid 湖南大学 2024-05-07 CN claimed
CN-116023232-B Preparation method of propyl malonic acid and homologs thereof 湖南省湘中制药有限公司 2024-03-08 CN claimed
CN-116730832-A Preparation method of 2-propyl caproic acid 湖南大学 2023-09-12 CN claimed
CN-116023232-A Preparation method of propyl malonic acid and homologs thereof 湖南省湘中制药有限公司 2023-04-28 CN claimed
EP-4116351-A1 METHOD FOR MANUFACTURING POLYURETHANE RIGID FOAMS BASF SE (DE) 2023-01-11 EP claimed
EP-3310835-B1 METHOD FOR MANUFACTURING POLYURETHANE RIGID FOAMS BASF SE (DE) 2022-09-07 EP claimed
US-20180186924-A1 METHOD FOR PRODUCING A RIGID POLYURETHANE FOAM BASF SE (DE) 2018-07-05 US claimed
EP-3310835-A1 METHOD FOR PRODUCING A RIGID POLYURETHANE FOAM BASF SE (DE) 2018-04-25 EP claimed
WO-2016202912-A1 METHOD FOR PRODUCING A RIGID POLYURETHANE FOAM BASF SE (DE) 2016-12-22 WO claimed
US-9365596-B2 Method for preparing quaternary phosphonium salts MICROVAST POWER SYSTEMS CO., LTD. (CN) 2016-06-14 US claimed
US-20150166587-A1 METHOD FOR PREPARING QUATERNARY PHOSPHONIUM SALTS MICROVAST POWER SYSTEMS CO., LTD. (CN) 2015-06-18 US claimed
US-12359017-B2 Method for producing a rigid polyurethane foam BASF SE (DE) 2025-07-15 US disclosed
WO-2025052748-A1 METHOD FOR PRODUCING SOLID ELECTROLYTIC CAPACITOR 株式会社カーリット 2025-03-13 WO disclosed
CN-118373735-B Valproic acid prepared by cyanoacetic acid ester method 湖南省湘中制药有限公司 2025-02-21 CN disclosed
EP-0062118-A1 Process for producing 1,3-dithiol-2-ylidene malonates NIHON NOHYAKU CO., LTD. (JP) 1982-10-13 EP disclosed
EP-0062119-A1 Process of producing 1,3-dithiol-2-ylidene malonic acid dialkyl esters NIHON NOHYAKU CO., LTD. (JP) 1982-10-13 EP disclosed
US-4329479-A FROM 1,1-DIHALDETHYLENE REACTED WITH A DIALKYLCARBONYLKETENE DIMERCAPTIDE NIHON NOHYAKU CO., LTD. (JP) 1982-05-11 US disclosed
US-4327223-A USING A TRIHALOGENOETHANE NIHON NOHYAKU CO., LTD. (JP) 1982-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166587-A1 METHOD FOR PREPARING QUATERNARY PHOSPHONIUM SALTS PHPT1, PHOSPHO1, PTEN MGAM 4027/4885GAA 4000/4885SI 1489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.