Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542544 | 0.83 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL26296600 | 0.81 | ASAH1 (0.62) | LMNA | |
| SCHEMBL14996273 | 0.81 | CTSL (0.57) | NPC1RAB9ASMN1; SMN2LMNACTSK | |
| SCHEMBL15109512 | 0.81 | CTSL (0.57) | NPC1RAB9ASMN1; SMN2LMNACTSK | |
| SCHEMBL16790930 | 0.81 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24095976 | 0.81 | HPGD (0.54) | NAAA | |
| SCHEMBL18286924 | 0.80 | CTSK (0.51) | NPC1RAB9ASMN1; SMN2LMNACTSK | |
| SCHEMBL24095742 | 0.78 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2LMNACTSK | |
| SCHEMBL28969065 | 0.78 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28969034 | 0.78 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |