Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.64 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270877 | 0.92 | FAAH (0.69) | FAAHCASP2HSP90AA1MEN1KMT2A | |
| SCHEMBL17002032 | 0.88 | FAAH (0.64) | FAAHCASP2HSP90AA1MEN1KMT2A | |
| SCHEMBL22927096 | 0.86 | FAAH (0.62) | FAAHHSP90AA1MEN1KMT2ADNM1 | |
| SCHEMBL21340423 | 0.85 | CASP2 (0.50) | FAAHCASP2MEN1KMT2AGAA | |
| SCHEMBL24096258 | 0.85 | FAAH (0.68) | FAAHCASP2HSP90AA1MEN1KMT2A | |
| SCHEMBL10316758 | 0.85 | FAAH (0.60) | FAAHCASP2HSP90AA1MEN1KMT2A | |
| SCHEMBL18896232 | 0.84 | FAAH (0.53) | FAAHCASP2HSP90AA1MEN1KMT2A | |
| SCHEMBL24096007 | 0.84 | FAAH (0.55) | FAAHCASP2HSP90AA1MEN1KMT2A | |
| SCHEMBL22341393 | 0.82 | CASP2 (0.66) | FAAHCASP2HSP90AA1DNM1EPHX2 | |
| SCHEMBL23619536 | 0.82 | FAAH (0.77) | FAAHMEN1KMT2AEPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |