Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.56 |
| ▸ | KDM4A | O75164 | 2/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.56 |
| ▸ | TET3 | O43151 | 1/20 | 0.56 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748334 | 0.87 | TSHR (0.48) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL17055793 | 0.82 | TSHR (0.52) | TSHRSLC1A1CA1CA2KDM4E | |
| SCHEMBL4057765 | 0.82 | TSHR (0.52) | TSHRSLC1A1CA1CA2KDM4E | |
| SCHEMBL14436811 | 0.82 | TSHR (0.52) | TSHRSLC1A1CA1CA2KDM4E | |
| SCHEMBL1296430 | 0.81 | TET2 (0.61) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL27642794 | 0.80 | TET2 (0.54) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL2821456 | 0.79 | FOLH1 (0.50) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL712283 | 0.77 | CYP1A2 (0.60) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL10254859 | 0.77 | CYP1A2 (0.60) | TET2KDM2AKDM4AKDM4CTET3 | |
| SCHEMBL27465091 | 0.77 | TET2 (0.56) | TET2KDM2AKDM4AKDM4CTET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106546-A1 | A PROCESS FOR THE PREPARATION OF ROSUVASTATIN INTERMEDIATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-09-01 | — | — | WO | disclosed |
| EP-1985300-A2 | A compound for re-equilibrating the intestinal bacterial flora with an antidiarrhoeic, anti-inflammatory and lentive activity against lactose and lactose derivative intolerances | Farmaceutici S.R.L. (IT) | 2008-10-29 | — | — | EP | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |