Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055793 | 1.00 | TSHR (0.52) | TSHRSLC1A1KMT2AMEN1LMNA | |
| SCHEMBL14436811 | 1.00 | TSHR (0.52) | TSHRSLC1A1KMT2AMEN1LMNA | |
| SCHEMBL10425792 | 0.87 | TSHR (0.56) | TSHRSLC1A1KMT2AMEN1LMNA | |
| SCHEMBL27710501 | 0.85 | L3MBTL1 (0.51) | TSHRKMT2AKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL3019317 | 0.85 | L3MBTL1 (0.47) | TSHRSLC1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL27797971 | 0.84 | L3MBTL1 (0.53) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL9668938 | 0.82 | TSHR (0.43) | TSHRSLC1A1KMT2AMEN1LMNA | |
| SCHEMBL7588140 | 0.82 | CYP2D6 (0.38) | TSHRKMT2AMEN1CA12CA14 | |
| SCHEMBL2409644 | 0.82 | TET2 (0.56) | TSHRSLC1A1KDM4ECA1CA2 | |
| SCHEMBL14436820 | 0.82 | TET2 (0.56) | TSHRSLC1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947659-A | Vegetable oil polyalcohol as well as preparation method and application thereof | 张家港市飞航科技有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-110143906-A | A kind of preparation method of the cis- -4- methyl-L-proline methyl esters of medicine intermediate N-Boc- | 深圳市老年医学研究所 | 2019-08-20 | — | — | CN | claimed |
| CN-115947659-B | Vegetable oil polyol and preparation method and application thereof | 张家港市飞航科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| US-11911488-B2 | Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy | THE JOHNS HOPKINS UNIVERSTY (US) | 2024-02-27 | — | — | US | disclosed |
| CN-115947659-A | Vegetable oil polyalcohol as well as preparation method and application thereof | 张家港市飞航科技有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-11241455-B2 | Methods of treating disease by metabolic control of T-cell differentiation | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2022-02-08 | — | — | US | disclosed |
| CN-107980042-B | Aryldihydro-2H-benzo [ b ] [1,4] oxazine sulfonamides and related compounds as ROR gamma agonists and for the treatment of disease | 莱斯拉公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |
| US-11078166-B2 | Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for PSMA-targeted imaging agents and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200360542-A1 | SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY | THE JOHNS HOPKINS UNIVERSTY | 2020-11-19 | — | — | US | disclosed |
| US-10736974-B2 | Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-08-11 | — | — | US | disclosed |
| CN-106132422-A | Adoptive cell therapy using agonists of retinoic acid receptor-associated orphan receptor gamma & related therapeutic methods | 莱斯拉公司 | 2016-11-16 | — | — | CN | disclosed |
| WO-2015120272-A1 | ORGANIC ACIDS AS GROWTH INHIBITORS OF PATHOLOGICAL CALCIFICATION AND USES THEREOF | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-08-13 | — | — | WO | disclosed |
| US-20150216825-A1 | ORGANIC ACIDS AS GROWTH INHIBITORS OF PATHOLOGICAL CALCIFICATION AND USES THEREOF | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-08-06 | — | — | US | disclosed |
| EP-2109646-A1 | CYANOACRYLIC ACID ESTER ADHESIVE CONTAINING POLYESTER AND A PLASTICIZER | Henkel AG & Co. KGaA (DE) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008086915-A1 | CYANOACRYLIC ACID ESTER ADHESIVE CONTAINING POLYESTER AND A PLASTICIZER | HENKEL AG & CO. KGAA (DE) | 2008-07-24 | — | — | WO | disclosed |
| CN-1215835-C | Ketone derivatives and medical use thereof | TORAY INDUSTRIES (JP) | 2005-08-24 | — | — | CN | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| CN-1194580-A | Ketone derivatives and medical use thereof | TORAY INDUSTRIES (JP) | 1998-09-30 | — | — | CN | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078166-B2 | Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for PSMA-targeted imaging agents and uses thereof | PAICS, FOLH1, UTS2R | TSHR 198/4885SLC1A1 1501/4885KMT2A 2425/4885 |
| US-20200360542-A1 | SCAFFOLDS AND MULTIFUNCTIONAL INTERMEDIATES FOR IMAGING PSMA AND CANCER THERAPY | FOLH1, PSMA3, PSMA7 | TSHR 4221/4885SLC1A1 1111/4885KMT2A 3647/4885 |
| US-11911488-B2 | Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy | FOLH1, PSMA3, PSMA7 | TSHR 4221/4885SLC1A1 1111/4885KMT2A 3647/4885 |
| US-10736974-B2 | Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy | FOLH1, PSMA3, PSMA7 | TSHR 4221/4885SLC1A1 1111/4885KMT2A 3647/4885 |
| US-11241455-B2 | Methods of treating disease by metabolic control of T-cell differentiation | GOT1, IL17A, OGDH | TSHR 3785/4885SLC1A1 672/4885KMT2A 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.