Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409644 | 0.87 | TET2 (0.56) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL10425792 | 0.83 | TSHR (0.56) | TSHRALDH1A1LMNACA1CA2 | |
| SCHEMBL27447240 | 0.81 | ENPEP (0.34) | TSHRALDH1A1TET2KDM4AKDM4C | |
| SCHEMBL27730935 | 0.80 | FFAR4 (0.39) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL9794608 | 0.79 | TSHR (0.48) | TSHRALDH1A1LMNASLC22A6ENPEP | |
| SCHEMBL710385 | 0.79 | TSHR (0.48) | TSHRALDH1A1FFAR4FFAR1LMNA | |
| SCHEMBL27730932 | 0.79 | CYP1A2 (0.50) | TSHRALDH1A1CA1CA2 | |
| SCHEMBL29253175 | 0.78 | CA1 (0.41) | TSHRFFAR1CA1CA2GPR84 | |
| SCHEMBL7947554 | 0.78 | CA2 (0.61) | TSHRFFAR1LMNACA1CA2 | |
| SCHEMBL149523 | 0.78 | CA2 (0.61) | TSHRFFAR1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113190-A1 | METHOD FOR THE PRODUCTION OF R-HYDROXYCARBOXYLIC ACIDS | EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) | 2008-09-25 | — | — | WO | claimed |