Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096486 | 0.83 | SRC (0.50) | PIK3CDPIK3CBPIK3CGSRCEGFR | |
| SCHEMBL14617706 | 0.75 | CSF1R (0.42) | PIK3CDPIK3CBPIK3CGSRCEGFR | |
| SCHEMBL29042116 | 0.73 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL29638715 | 0.73 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL23997145 | 0.73 | SRC (0.55) | PIK3CDPIK3CBPIK3CGSRCEGFR | |
| SCHEMBL30320501 | 0.73 | SRC (0.55) | PIK3CDPIK3CBPIK3CGSRCEGFR | |
| SCHEMBL3716785 | 0.72 | EGFR (0.72) | SRCEGFRKDM4E | |
| SCHEMBL4826570 | 0.72 | SRC (0.67) | PIK3CDPIK3CBPIK3CGSRCEGFR | |
| SCHEMBL23057484 | 0.71 | EGFR (0.42) | PIK3CDPIK3CBPIK3CGSRCEGFR | |
| SCHEMBL10260251 | 0.71 | PIK3CD (0.52) | PIK3CDPIK3CBPIK3CGSRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252488-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |