Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 11/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAST3 | O60307 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096714 | 1.00 | MAPK8 (0.35) | MAPK8JAK3IDH1IDH2MAPK9 | |
| SCHEMBL24096869 | 0.83 | HDAC4 (0.46) | IDH1HDAC4HDAC6USP30 | |
| SCHEMBL24096892 | 0.83 | HDAC4 (0.46) | IDH1HDAC4HDAC6USP30 | |
| SCHEMBL24096718 | 0.82 | HDAC4 (0.34) | IDH1SYKHDAC4HDAC6USP30 | |
| SCHEMBL24096721 | 0.82 | HDAC4 (0.34) | IDH1SYKHDAC4HDAC6USP30 | |
| SCHEMBL24096794 | 0.81 | PIM1 (0.39) | MAPK8JAK3IDH1MAST3 | |
| SCHEMBL24096793 | 0.81 | PIM1 (0.39) | MAPK8JAK3IDH1MAST3 | |
| SCHEMBL24096860 | 0.79 | JAK3 (0.35) | JAK3IDH1IDH2 | |
| SCHEMBL24096864 | 0.79 | JAK3 (0.35) | JAK3IDH1IDH2 | |
| SCHEMBL24096773 | 0.75 | MAPK8 (0.41) | MAPK8MAPK9MAST3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |