Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | POLR1A | O95602 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096721 | 1.00 | HDAC4 (0.34) | HDAC4HDAC6SYKIDH1USP30 | |
| SCHEMBL24096892 | 0.85 | HDAC4 (0.46) | HDAC4HDAC6IDH1USP30ADORA1 | |
| SCHEMBL24096869 | 0.85 | HDAC4 (0.46) | HDAC4HDAC6IDH1USP30ADORA1 | |
| SCHEMBL24096714 | 0.82 | MAPK8 (0.35) | HDAC4HDAC6SYKIDH1USP30 | |
| SCHEMBL24096728 | 0.82 | MAPK8 (0.35) | HDAC4HDAC6SYKIDH1USP30 | |
| SCHEMBL24096823 | 0.76 | CDK2 (0.37) | POLR1AJAK1PIK3CD | |
| SCHEMBL24096739 | 0.74 | BTK (0.46) | HDAC4HDAC6USP30ADORA1PIK3CD | |
| SCHEMBL24096735 | 0.74 | BTK (0.46) | HDAC4HDAC6USP30ADORA1PIK3CD | |
| SCHEMBL24096927 | 0.73 | JAK3 (0.36) | USP30POLR1AGRIA1ADORA1FPR3 | |
| SCHEMBL24096795 | 0.73 | USP30 (0.42) | HDAC4HDAC6USP30ADORA1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |