Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30841573 | 0.81 | BTK (0.49) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL24096860 | 0.81 | JAK3 (0.35) | BTKIDH1 | |
| SCHEMBL24096864 | 0.81 | JAK3 (0.35) | BTKIDH1 | |
| SCHEMBL24096960 | 0.81 | HDAC4 (0.47) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL31639386 | 0.79 | USP30 (0.46) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL24096892 | 0.78 | HDAC4 (0.46) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL24096869 | 0.78 | HDAC4 (0.46) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL24096766 | 0.78 | HDAC4 (0.45) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL29072509 | 0.77 | MAPK3 (0.49) | HDAC4HDAC6BTKPARP1TRPV1 | |
| SCHEMBL29072510 | 0.77 | MAPK3 (0.49) | HDAC4HDAC6BTKPARP1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |