Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096869 | 0.84 | HDAC4 (0.46) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL24096892 | 0.84 | HDAC4 (0.46) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL24096760 | 0.81 | PIM1 (0.41) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL24096807 | 0.80 | BTK (0.40) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL24096717 | 0.78 | BTK (0.41) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL24096753 | 0.78 | HDAC4 (0.45) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL24096960 | 0.78 | HDAC4 (0.47) | HDAC4HDAC6TRPV1BTKUSP30 | |
| SCHEMBL31639386 | 0.76 | USP30 (0.46) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL26180095 | 0.76 | PIM1 (0.48) | HDAC4HDAC6TRPV1BTKPIM1 | |
| SCHEMBL269817 | 0.75 | FPR2 (0.48) | HDAC4HDAC6TRPV1BTKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |