Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 7/20 | 0.39 |
| ▸ | JAK1 | P23458 | 7/20 | 0.39 |
| ▸ | JAK3 | P52333 | 7/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096726 | 0.84 | PIM1 (0.40) | PIM1PIM2MARK3MAP4K2CAMK2B | |
| SCHEMBL24096809 | 0.82 | PIM1 (0.40) | PIM1PIM2MARK3MAP4K2CAMK2B | |
| SCHEMBL24096766 | 0.81 | HDAC4 (0.45) | PIM1PIM2BRD4HDAC4HDAC6 | |
| SCHEMBL24096827 | 0.80 | PIM1 (0.41) | PIM1PIM2MARK3MAP4K2CAMK2B | |
| SCHEMBL24096842 | 0.76 | USP30 (0.41) | PIM1PIM2MARK3MAP4K2CAMK2B | |
| SCHEMBL24096628 | 0.75 | USP30 (0.42) | PIM1PIM2MARK3MAP4K2CAMK2B | |
| SCHEMBL24096794 | 0.73 | PIM1 (0.39) | PIM1PIM2MARK3MAP4K2CAMK2B | |
| SCHEMBL24096725 | 0.73 | CDK2 (0.47) | PIM1PIM2HDAC4HDAC6USP30 | |
| SCHEMBL29283741 | 0.73 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL29283742 | 0.73 | TRPV1 (0.49) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249417-A1 | HETEROCYCLIC COMPOUND AND DERIVATIVE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2021-12-16 | — | — | WO | disclosed |