Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | CDK4 | P11802 | 4/20 | 0.56 |
| ▸ | CCND1 | P24385 | 4/20 | 0.56 |
| ▸ | HTR6 | P50406 | 4/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060777 | 0.80 | HTR2C (1.00) | HTR2AHTR2CCDK4CCND1HTR6 | |
| SCHEMBL3990419 | 0.74 | HTR2C (0.81) | HTR2AHTR2CCDK4CCND1HTR1D | |
| SCHEMBL2036331 | 0.74 | HTR2A (0.70) | HTR2AHTR2CCDK4CCND1HTR6 | |
| SCHEMBL11366447 | 0.74 | CDK4 (1.00) | HTR2AHTR2CCDK4CCND1HTR6 | |
| Hydrochloric Acid SCHEMBL11486417 | 0.73 | HTR2A (0.78) | HTR2AHTR2CCDK4CCND1HTR1D | |
| SCHEMBL2404374 | 0.72 | KMT2A (0.55) | HTR2AHTR2CCDK4CCND1MTNR1A | |
| SCHEMBL29372496 | 0.71 | CDK4 (0.76) | HTR2AHTR2CCDK4CCND1HTR6 | |
| SCHEMBL3595410 | 0.71 | CDK4 (0.76) | HTR2AHTR2CCDK4CCND1HTR6 | |
| SCHEMBL1520197 | 0.70 | HTR2A (0.62) | HTR2AHTR2CCDK4CCND1MTNR1A | |
| SCHEMBL5333543 | 0.70 | CDK4 (0.61) | HTR2AHTR2CCDK4CCND1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | HTR2A 46/4885HTR2C 80/4885CDK4 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.