Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606015 | 0.86 | POLB (0.46) | MEN1KMT2APDGFRBFGFR1PDGFRA | |
| SCHEMBL2589956 | 0.83 | LMNA (0.52) | TDP1MEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL19557493 | 0.82 | ALDH1A1 (0.45) | TDP1MEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL1785981 | 0.81 | MEN1 (0.47) | TDP1MEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL2794810 | 0.80 | MAPT (0.49) | MEN1KMT2AMAPTRAB9AS1PR4 | |
| SCHEMBL2795160 | 0.79 | TDP1 (0.46) | TDP1MEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL1787152 | 0.77 | LMNA (0.52) | TDP1MEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL19035920 | 0.76 | HTT (0.43) | TDP1MEN1KMT2APDGFRBFGFR1 | |
| SCHEMBL24100428 | 0.76 | TDP1 (0.51) | TDP1MEN1KMT2AKDM4EPDGFRB | |
| SCHEMBL2903296 | 0.75 | TDP1 (0.53) | TDP1MEN1KMT2AKDM4EPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |