Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10292125 | 1.00 | SMYD3 (0.33) | SMYD3OPRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL5561348 | 0.88 | — | — | |
| SCHEMBL13006777 | 0.88 | GNAI3 (0.42) | OPRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL27340884 | 0.88 | GNAI3 (0.42) | OPRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL11804796 | 0.88 | GNAI3 (0.42) | OPRM1GNAI3GNAO1GNAI1 | |
| Ammonia Solution, Strong SCHEMBL20492540 | 0.85 | — | — | |
| Hydrogen Sulfide SCHEMBL5676322 | 0.85 | — | — | |
| SCHEMBL8840566 | 0.81 | SHBG (0.34) | SMYD3 | |
| SCHEMBL2404767 | 0.81 | SHBG (0.34) | SMYD3 | |
| SCHEMBL25935950 | 0.81 | SHBG (0.34) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| US-20200048195-A1 | SUBSTITUTED PYRROLIDINE CARBOXAMIDE COMPOUNDS | Epizyme, Inc. | 2020-02-13 | — | — | US | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| US-9273200-B2 | Propylene polymer composition and molded article thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-01 | — | — | US | disclosed |
| US-20140256869-A1 | PROPYLENE POLYMER COMPOSITION AND MOLDED ARTICLE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-09-11 | — | — | US | disclosed |
| US-8592071-B2 | Laminated porous film and separator for battery | MITSUBISHI PLASTICS, INC. (JP) | 2013-11-26 | — | — | US | disclosed |
| US-20110212358-A1 | LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY | MITSUBISHI PLASTICS, INC. (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-1369221-B9 | SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF | NEW JAPAN CHEM CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7682689-B2 | A polypropylene-based resin and a beta-crystal nucleating agent having a film thickness uniformity of < 0.1 and the film exhibiting good stability; high air-permeability and porosity; good feeling and electrical resistance required for a battery separator; industrial scale; | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| EP-1369221-B1 | SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF | NEW JAPAN CHEM CO LTD (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-0557721-B1 | Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. | NEW JAPAN CHEM CO LTD (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0790262-B1 | PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF | CHISSO CORP (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-6005034-A | POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS | CHISSO CORPOATION (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0962489-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5716998-A | PARTICLES COMPRISING POLYPROPYLENE RESIN AND DIAMIDE COMPOUND AS BETA-FORM NUCLEATING AGENT | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0790262-A1 | PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF | CHISSO CORPORATION (JP) | 1997-08-20 | — | — | EP | disclosed |
| EP-0790275-A1 | PREFOAMED PARTICLES OF POLYPROPYLENE RESIN AND PROCESS FOR PRODUCING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-5491188-A | ADDING DIAMIDE COMPOUNDS AS NUCLEATING AGENT TO PROPYLENE HOMO-, CO- AND TERPOLYMERS; FILTRATION MEMBRANES, PRINTING SHEETS | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0632095-A2 | Porous stretched article of polypropylene-based resin and process for its preparation | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0557721-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | SMYD3 1/4885OPRM1 3823/4885GNAI3 224/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | SMYD3 2/4885OPRM1 2873/4885GNAI3 245/4885 |
| US-20200048195-A1 | SUBSTITUTED PYRROLIDINE CARBOXAMIDE COMPOUNDS | SMYD3, SMYD2, SMURF2 | SMYD3 1/4885OPRM1 2620/4885GNAI3 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.