Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | QPCT | Q16769 | 1/20 | 0.59 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.59 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179016 | 0.88 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL30523909 | 0.88 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL30523908 | 0.88 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL23257635 | 0.84 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL7994218 | 0.83 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| Hydrochloric Acid SCHEMBL31039428 | 0.82 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| Hydrochloric Acid SCHEMBL20565749 | 0.82 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL5610972 | 0.81 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL1509681 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL9131912 | 0.80 | CYP19A1 (0.70) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8646616-B2 | Composite membrane with coating comprising polyalkylene oxide and imidazol compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-11 | — | — | US | disclosed |
| WO-2011149572-A1 | POLYAMIDE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110284454-A1 | COMPOSITE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-24 | — | — | US | disclosed |
| EP-0733366-B1 | Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics | DU PONT (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0324377-B1 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | DU PONT (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0733366-A2 | Pharmaceutical compositions comprising angiotensin II receptor blocking imidazoles and diuretics | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0253310-B1 | Angiotensin II receptor blocking imidazoles | DU PONT (US) | 1994-10-26 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |
| US-5155118-A | Administering angiotensin inhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-5153197-A | Treatment of hypertension with angiotensin II blocking imidazoles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| US-5138069-A | Treating hypertension and congestive heart failure | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| EP-0127114-B1 | PROCESS FOR THE CLEAVAGE OF PHTHALIMIDES | BASF Aktiengesellschaft (DE) | 1986-10-29 | — | — | EP | disclosed |
| US-4544755-A | HYDROLYSIS WITH ALKANOLAMINE | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| EP-0127114-A1 | Process for the cleavage of phthalimides | BASF Aktiengesellschaft (DE) | 1984-12-05 | — | — | EP | disclosed |
| US-4006243-A | FUNGICIDE, BACTERICIDE, YEAST | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |