Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.58 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31039428 | 0.98 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| Hydrochloric Acid SCHEMBL20565749 | 0.98 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL30523908 | 0.91 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL15179016 | 0.91 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL30523909 | 0.91 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL241 | 0.84 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL27311222 | 0.83 | CYP19A1 (0.56) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL20622756 | 0.82 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| SCHEMBL17450431 | 0.82 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 | |
| Iodide SCHEMBL28192688 | 0.81 | CYP11B1 (0.97) | CYP11B1CYP11B2CYP19A1POLBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628045-B1 | COMPOUNDS | UNIV SHEFFIELD (GB) | 2024-07-03 | — | — | EP | disclosed |
| US-20210113534-A1 | COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113534-A1 | COMPOUNDS | MRGPRX2, MC2R, ADM2 | CYP11B1 321/4885CYP11B2 239/4885CYP19A1 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.