Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789228 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL21674083 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MAPTRAB9AL3MBTL1 | |
| SCHEMBL19306009 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL30873828 | 0.84 | MEN1 (0.56) | SMN1; SMN2ALDH1A1MAPTGFERNPC1 | |
| SCHEMBL22411255 | 0.84 | MEN1 (0.56) | SMN1; SMN2ALDH1A1MAPTGFERNPC1 | |
| SCHEMBL27804334 | 0.82 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL23063966 | 0.81 | HTT (0.46) | SMN1; SMN2ALDH1A1MAPTGFERNPC1 | |
| SCHEMBL28455434 | 0.81 | MAPT (0.61) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL21674105 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTL3MBTL1HTT | |
| SCHEMBL1479187 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |