Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135797 | 0.79 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL30312332 | 0.74 | PIKFYVE (0.51) | PIK3CDPIK3CAPIK3CBMTORKDM4E | |
| SCHEMBL23272151 | 0.74 | PIKFYVE (0.51) | PIK3CDPIK3CAPIK3CBMTORKDM4E | |
| SCHEMBL21135798 | 0.71 | PIK3CA (0.41) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL17708307 | 0.71 | PIK3CA (0.51) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL16727864 | 0.69 | PIK3CA (0.56) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL23139995 | 0.68 | NUDT1 (0.40) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL16611524 | 0.67 | PIK3CA (0.60) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL17708308 | 0.66 | PIK3CA (0.43) | PIK3CDPIK3CAPIK3R1PIK3CGPIK3CB | |
| SCHEMBL21055523 | 0.66 | PIKFYVE (0.54) | PIK3CDPIK3CAPIK3CBMTORKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252895-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |