Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692654 | 0.87 | HCAR3 (0.71) | HCAR3KDM4EMAPTHCAR2 | |
| SCHEMBL12380464 | 0.86 | HCAR3 (0.60) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL1345024 | 0.85 | HCAR3 (0.54) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL9592348 | 0.85 | HCAR3 (0.70) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL11565569 | 0.85 | SMN1; SMN2 (0.56) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL214930 | 0.84 | LMNA (0.51) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL17365710 | 0.84 | HCAR3 (0.71) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL28287682 | 0.84 | HCAR3 (0.55) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL9128629 | 0.84 | HCAR3 (0.49) | HCAR3RAB9ANPC1KDM4EMAPT | |
| SCHEMBL28287681 | 0.84 | HCAR3 (0.55) | HCAR3RAB9ANPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |