Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045331 | 0.88 | CTSK (0.48) | AAK1HDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL22012933 | 0.85 | CA1 (0.48) | AAK1HDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL22012931 | 0.85 | CA1 (0.48) | AAK1HDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL24103846 | 0.82 | HDAC4 (0.50) | AAK1HDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL27592207 | 0.80 | RAB9A (0.43) | AAK1RAB9ANPC1MAPTTSHR | |
| SCHEMBL6615111 | 0.80 | RAB9A (0.43) | AAK1RAB9ANPC1MAPTTSHR | |
| SCHEMBL17571407 | 0.75 | TSHR (0.56) | NPC1MAPTCTSKCTSSTSHR | |
| SCHEMBL29372377 | 0.74 | RAB9A (0.51) | RAB9ANPC1MAPTALDH1A1TSHR | |
| SCHEMBL283737 | 0.74 | RAB9A (0.51) | RAB9ANPC1MAPTALDH1A1TSHR | |
| SCHEMBL5047380 | 0.73 | CTSK (0.46) | HDAC4HDAC1HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021250194-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2021-12-16 | — | — | WO | disclosed |