Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24105882 | 0.97 | ALKBH5 (0.58) | ALKBH5FTOMEN1NPC1HCRTR1 | |
| SCHEMBL14931060 | 0.88 | HSD17B10 (0.46) | ALKBH5FTOPDCD1CD274HSD17B10 | |
| SCHEMBL21156638 | 0.86 | HSD17B10 (0.44) | ALKBH5FTOMEN1NPC1RAB9A | |
| SCHEMBL18015005 | 0.81 | ALKBH5 (0.56) | ALKBH5FTOKMT2AKDM4EHSD17B10 | |
| SCHEMBL26242847 | 0.80 | HSD17B10 (0.41) | ALKBH5FTOKDM4EPDCD1CD274 | |
| SCHEMBL21157928 | 0.80 | L3MBTL1 (0.44) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL14931058 | 0.80 | ALKBH5 (0.72) | ALKBH5FTOMEN1NPC1HCRTR1 | |
| SCHEMBL21157926 | 0.79 | HSD17B10 (0.40) | ALKBH5FTOHSD17B10BRD4HSD11B1 | |
| SCHEMBL17030436 | 0.78 | HSD17B10 (0.46) | ALKBH5FTOMEN1KMT2AKDM4E | |
| SCHEMBL18160217 | 0.78 | ALKBH5 (0.65) | ALKBH5FTOMEN1NPC1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210388013-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210388013-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ODC1, OCIAD1, OCIAD2 | ALKBH5 1044/4885FTO 69/4885MEN1 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.