Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 6/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110608 | 0.80 | RPS6KA5 (0.35) | IRAK4RPS6KA5RPS6KA4EGFR | |
| SCHEMBL24109815 | 0.78 | RPS6KA5 (0.41) | IRAK4RPS6KA5RPS6KA4 | |
| SCHEMBL24110237 | 0.77 | MKNK2 (0.39) | IRAK4EGFRCDK4CDK6 | |
| SCHEMBL24110132 | 0.76 | RPS6KA5 (0.35) | IRAK4RPS6KA5RPS6KA4EGFR | |
| SCHEMBL24110238 | 0.75 | MAPT (0.39) | CDK4CDK6 | |
| SCHEMBL24110147 | 0.72 | CDC7 (0.35) | CDK4CDK6 | |
| SCHEMBL24110242 | 0.72 | ELANE (0.38) | IRAK4 | |
| SCHEMBL24109904 | 0.68 | DRD2 (0.49) | CDK4 | |
| SCHEMBL24109896 | 0.66 | HRH3 (0.31) | — | |
| SCHEMBL256382 | 0.66 | RPS6KA5 (0.45) | RPS6KA5RPS6KA4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| WO-2021252692-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | IRAK4 4512/4885RPS6KA5 1745/4885RPS6KA4 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.