Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.48 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493155 | 1.00 | ALOX5 (0.56) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL3493080 | 1.00 | ALOX5 (0.56) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL11213402 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL301664 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL10884586 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL24354392 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL3491458 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL17779527 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL21972780 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL11414522 | 0.98 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102863341-B | Chemical synthesis method of (1R, 2S)-2-aryl cyclopropylamine derivative | UNIV NANTONG | 2014-05-07 | — | — | CN | claimed |
| CN-102863341-A | Chemical synthesis method of (1R, 2S)-2-aryl cyclopropylamine derivative | UNIV NANTONG | 2013-01-09 | — | — | CN | claimed |
| US-20100331575-A1 | Processes For The Preparation Of Optically Active Intermediates | ASTRAZENECA AB (SE) | 2010-12-30 | — | — | US | claimed |
| US-7790927-B2 | Using hypochlorite in water in presence of alkali metal hydroxide | ASTRAZENECA AB (SE) | 2010-09-07 | — | — | US | claimed |
| US-20090221462-A1 | Fragrance compositions | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2009-09-03 | — | — | US | claimed |
| CN-101495444-A | A process for the preparation of optically active cyclopropylamines | ASTRAZENECA AB (SE) | 2009-07-29 | — | — | CN | claimed |
| EP-2049463-A1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOPROPYLAMINES | Astra Zeneca AB (SE) | 2009-04-22 | — | — | EP | claimed |
| US-20080071114-A1 | Processes For The Preparation Of Optically Active Intermediates | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | US | claimed |
| WO-2008018823-A1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOPROPYLAMINES | ASTRAZENECA AB (SE) | 2008-02-14 | — | — | WO | claimed |
| WO-2006131739-A1 | FRAGRANCE COMPOSITIONS | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2006-12-14 | — | — | WO | claimed |
| EP-0015604-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITION OF LIPOGENESIS IN MAMMALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-02-23 | — | — | EP | claimed |
| JP-10165132-A | — | — | None | — | — | JP | disclosed |
| CN-118599598-A | Perfume composition | 小川香料株式会社 | 2024-09-06 | — | — | CN | disclosed |
| EP-2668255-B1 | MALODOR NEUTRALIZING COMPOSITIONS COMPRISING BORNYL ACETATE OR ISOBORNYL ACETATE | ROBERTET INC (US) | 2020-08-12 | — | — | EP | disclosed |
| CN-102883602-B | Method for reducing virulence of bacteria | UWM研究基金会有限公司 | 2017-07-18 | — | — | CN | disclosed |
| US-4528142-A | 1-Hydroxymethyl-2-acyl cyclopropane derivatives and esters thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-07-09 | — | — | US | disclosed |
| US-4500448-A | PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-02-19 | — | — | US | disclosed |
| US-4481225-A | ACETATE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-11-06 | — | — | US | disclosed |
| US-4435428-A | Use in augmenting or enhancing the aroma or taste of foodstuff or chewing gum with the methyl carbonate of 1-hydroxymethyl-2-heptanoyl cyclopropane | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-03-06 | — | — | US | disclosed |
| US-3991123-A | PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080071114-A1 | Processes For The Preparation Of Optically Active Intermediates | DHPS, CYP1B1, CYP2S1 | ALOX5 480/4885GABRR1 533/4885GABRR2 532/4885 |
| US-20100331575-A1 | Processes For The Preparation Of Optically Active Intermediates | DHPS, CYP1B1, CYP2S1 | ALOX5 480/4885GABRR1 533/4885GABRR2 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.