Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 6/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25450726 | 0.97 | PTK6 (0.38) | PTK6LCKAURKBTTK | |
| Trifluoroacetic Acid SCHEMBL28982207 | 0.94 | PTK6 (0.36) | PTK6TTK | |
| SCHEMBL30171624 | 0.91 | PTK6 (0.44) | PTK6LCKAURKBTTK | |
| SCHEMBL22123122 | 0.91 | PTK6 (0.44) | PTK6LCKAURKBTTK | |
| SCHEMBL30386185 | 0.89 | PTK6 (0.40) | PTK6LCKAURKBTTK | |
| SCHEMBL25450694 | 0.89 | PTK6 (0.40) | PTK6LCKAURKBTTK | |
| SCHEMBL25176442 | 0.88 | PTK6 (0.40) | PTK6LCKAURKB | |
| Iodide SCHEMBL28982230 | 0.88 | PTK6 (0.39) | PTK6LCKAURKB | |
| SCHEMBL25176394 | 0.87 | PTK6 (0.39) | PTK6LCK | |
| SCHEMBL24112330 | 0.87 | PTK6 (0.39) | PTK6LCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |