Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 15/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.31 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25176442 | 0.96 | PTK6 (0.40) | PTK6LCKEGFRERBB2ERBB3 | |
| Iodide SCHEMBL28982230 | 0.96 | PTK6 (0.39) | PTK6LCKEGFRERBB2ERBB3 | |
| SCHEMBL30171867 | 0.90 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL22123725 | 0.90 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL25450726 | 0.88 | PTK6 (0.38) | PTK6LCKAURKBMAPKAPK5 | |
| SCHEMBL24112356 | 0.87 | PTK6 (0.38) | PTK6LCKAURKB | |
| SCHEMBL28982185 | 0.87 | PTK6 (0.39) | PTK6LCKEGFR | |
| SCHEMBL30402918 | 0.86 | PTK6 (0.39) | PTK6LCKEGFR | |
| Trifluoroacetic Acid SCHEMBL30386113 | 0.85 | PTK6 (0.39) | PTK6LCKEGFRERBB2ERBB3 | |
| Trifluoroacetic Acid SCHEMBL28982207 | 0.85 | PTK6 (0.36) | PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |