Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCL6 | P41182 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349902 | 0.90 | PTK6 (0.41) | PTK6POLBBCL6IGF1RALK | |
| SCHEMBL22125118 | 0.90 | PTK6 (0.41) | PTK6POLBBCL6IGF1RALK | |
| SCHEMBL22124504 | 0.89 | PTK6 (0.42) | PTK6BCL6IGF1RALKMCHR1 | |
| SCHEMBL24112398 | 0.89 | PTK6 (0.44) | PTK6POLBMAPTBCL6IGF1R | |
| SCHEMBL24112596 | 0.89 | PTK6 (0.40) | PTK6POLBBCL6IGF1RPDE5A | |
| SCHEMBL25450750 | 0.88 | PTK6 (0.42) | PTK6BCL6IGF1RMCHR1KDM4E | |
| SCHEMBL22123365 | 0.88 | PTK6 (0.42) | PTK6BCL6IGF1RALKMCHR1 | |
| SCHEMBL22123532 | 0.88 | PTK6 (0.42) | PTK6BCL6IGF1RALKMCHR1 | |
| SCHEMBL22123658 | 0.88 | PTK6 (0.42) | PTK6BCL6IGF1RALKMCHR1 | |
| Hydrochloric Acid SCHEMBL30171699 | 0.88 | PTK6 (0.42) | PTK6BCL6IGF1RALKMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249896-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-16 | — | — | WO | disclosed |