Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112969 | 0.85 | CTSL (0.60) | CTSLCTSBCTSS | |
| SCHEMBL24112970 | 0.85 | CTSL (0.60) | CTSLCTSBCTSS | |
| SCHEMBL24740493 | 0.85 | CTSL (0.60) | CTSLCTSBCTSS | |
| SCHEMBL24020165 | 0.83 | CYP51A1 (0.44) | CTSLCTSBCTSS | |
| SCHEMBL21702265 | 0.77 | CYP51A1 (0.49) | — | |
| SCHEMBL26494098 | 0.77 | — | — | |
| SCHEMBL24020121 | 0.77 | CTSB (0.65) | CTSLCTSBCTSS | |
| SCHEMBL24020258 | 0.77 | CTSB (0.65) | CTSLCTSBCTSS | |
| SCHEMBL24020255 | 0.77 | CTSB (0.65) | CTSLCTSBCTSS | |
| SCHEMBL23836436 | 0.76 | CTSL (0.42) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |