Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112920 | 0.85 | GRIN2B (0.35) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL28149260 | 0.85 | JAK3 (0.36) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL28488407 | 0.82 | JAK3 (0.35) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL28149295 | 0.82 | CTSK (0.35) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL444287 | 0.82 | GRIN2B (0.37) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL442628 | 0.80 | GRIN2B (0.36) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL27092800 | 0.79 | GRIN2B (0.39) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL24112800 | 0.78 | GRIN2B (0.34) | JAK3GRIN2BGRIN2C | |
| SCHEMBL25255216 | 0.78 | GRIN2B (0.38) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL28717926 | 0.77 | JAK3 (0.34) | HPGDJAK3GRIN2BGRIN2CCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |