Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28149260 | 0.92 | JAK3 (0.36) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL28149295 | 0.87 | CTSK (0.35) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL442628 | 0.85 | GRIN2B (0.36) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL25255216 | 0.83 | GRIN2B (0.38) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL24112802 | 0.82 | HPGD (0.34) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL444287 | 0.82 | GRIN2B (0.37) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL27092800 | 0.79 | GRIN2B (0.39) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL28498279 | 0.79 | JAK3 (0.35) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL28717926 | 0.77 | JAK3 (0.34) | JAK3GRIN2BGRIN2CCTSKHPGD | |
| SCHEMBL27219428 | 0.76 | GRIN2B (0.37) | JAK3GRIN2BGRIN2CCTSKHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883238-B | Preparation method of alpha-azaspiro compound | 贵州医科大学 | 2020-12-18 | — | — | CN | disclosed |