Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281598 | 0.82 | ALOX15 (0.50) | ALOX15KMT2ADOT1LCREBBPKCNA6 | |
| SCHEMBL24740419 | 0.79 | ALOX15 (0.55) | ALOX15DAOKCNA6KCNA3KCNA4 | |
| SCHEMBL24019830 | 0.79 | ALOX15 (0.55) | ALOX15DAOKCNA6KCNA3KCNA4 | |
| SCHEMBL18136104 | 0.77 | DAO (0.38) | DAOKCNA6KCNA3KCNA4KCNA5 | |
| SCHEMBL3338566 | 0.76 | CYP1A2 (0.52) | DAO | |
| SCHEMBL11610001 | 0.74 | RAB9A (0.54) | KMT2ADAONPC1ALDH1A1 | |
| SCHEMBL2940426 | 0.74 | BLM (0.50) | ALOX15KMT2ADAOALDH1A1HPGD | |
| SCHEMBL11607578 | 0.74 | DAO (0.39) | ALOX15KMT2ADAOKCNA6KCNA3 | |
| SCHEMBL11612240 | 0.73 | NPC1 (0.58) | ALOX15DAONPC1PTPN11 | |
| SCHEMBL11609613 | 0.73 | KMT2A (0.52) | KMT2ADAONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |