Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25758891 | 0.85 | ALOX15 (0.54) | NUDT1ALOX15KMT2AKDM4ETP53 | |
| SCHEMBL30967478 | 0.82 | CYP1A2 (0.44) | MAPTKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL1255142 | 0.82 | CYP1A2 (0.44) | MAPTKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL30189256 | 0.81 | GRIN1 (0.50) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24113095 | 0.81 | GRIN1 (0.50) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24112871 | 0.80 | NUDT1 (0.47) | NUDT1ALOX15PTPN11CCNKCDK12 | |
| SCHEMBL31414518 | 0.79 | NUDT1 (0.55) | NUDT1ALOX15PTPN11CCNKCDK12 | |
| SCHEMBL30967524 | 0.79 | HIPK2 (0.43) | NUDT1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL20839976 | 0.78 | NUDT1 (0.63) | NUDT1ALOX15PTPN11CCNKCDK12 | |
| SCHEMBL24754486 | 0.76 | HRH4 (0.56) | NUDT1ALOX15PTPN11NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |