Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC5A7 | Q9GZV3 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407227 | 0.86 | MAPT (0.48) | ALOX5MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2407229 | 0.86 | MAPT (0.48) | ALOX5MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2468734 | 0.84 | ALOX5 (0.35) | ALOX5MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2468731 | 0.84 | ALOX5 (0.35) | ALOX5MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2409068 | 0.84 | ALOX5 (0.45) | ALOX5MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2409066 | 0.84 | ALOX5 (0.45) | ALOX5MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL2408654 | 0.83 | ACHE (0.54) | ALOX5MAPTBCHEACHE | |
| SCHEMBL2407869 | 0.83 | KDM4E (0.41) | ALOX5MAPTSMN1; SMN2ALDH1A1BCHE | |
| SCHEMBL2407867 | 0.83 | KDM4E (0.41) | ALOX5MAPTSMN1; SMN2ALDH1A1BCHE | |
| SCHEMBL2408651 | 0.83 | ACHE (0.54) | ALOX5MAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629277-B2 | Styrenyl 1,2,4-oxadiazole compounds | Piramal Enterprises Limited (IN) | 2014-01-14 | — | — | US | claimed |
| US-20130005771-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2013-01-03 | — | — | US | claimed |
| EP-2539327-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2013-01-02 | — | — | EP | claimed |
| WO-2011104680-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-09-01 | — | — | WO | claimed |
| US-8629277-B2 | Styrenyl 1,2,4-oxadiazole compounds | Piramal Enterprises Limited (IN) | 2014-01-14 | — | — | US | disclosed |
| US-20130005771-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2013-01-03 | — | — | US | disclosed |
| EP-2539327-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011104680-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005771-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | MCL1, OXA1L, ABL1 | ALOX5 918/4885MAPT 365/4885SMN1; SMN2 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.