Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113637 | 1.00 | GPR119 (0.47) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL19040815 | 1.00 | GPR119 (0.47) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL19040882 | 0.99 | GPR119 (0.47) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL19040791 | 0.95 | GPR119 (0.50) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL19032684 | 0.94 | GPR119 (0.43) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL19040709 | 0.91 | GNAI3 (0.42) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL23606531 | 0.91 | GNAI3 (0.42) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL19040848 | 0.90 | GNAI3 (0.41) | GPR119FAAHGNAI3GNAO1GNAI1 | |
| SCHEMBL11892884 | 0.90 | GPR119 (0.45) | GPR119FAAHKDM4EPKMHPGD | |
| SCHEMBL23576221 | 0.89 | GPR119 (0.47) | GPR119FAAHGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394030-B1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX INC (US) | 2021-12-22 | — | — | EP | disclosed |