Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960552 | 0.83 | KCNH2 (0.39) | PSMB5PSMB8LTB4RLTB4R2HTR2A | |
| SCHEMBL625415 | 0.83 | KCNH2 (0.39) | PSMB5PSMB8LTB4RLTB4R2HTR2A | |
| SCHEMBL28208317 | 0.82 | LTB4R (0.41) | PSMB5PSMB8LTB4RLTB4R2DRD2 | |
| SCHEMBL28207711 | 0.79 | LTB4R (0.39) | PSMB5PSMB8LTB4RLTB4R2DRD2 | |
| SCHEMBL12614330 | 0.77 | MAOB (0.61) | MAOBCYP19A1 | |
| SCHEMBL28001184 | 0.77 | CYP3A4 (0.42) | MAOBPPARGPPARDMEN1KMT2A | |
| SCHEMBL6099078 | 0.76 | LTB4R (0.47) | PSMB5PSMB8LTB4RLTB4R2DRD2 | |
| SCHEMBL2316931 | 0.76 | LTB4R (0.47) | PSMB5PSMB8LTB4RLTB4R2DRD2 | |
| SCHEMBL19574896 | 0.76 | LTB4R (0.44) | PSMB5LTB4RLTB4R2DRD2DRD3 | |
| SCHEMBL2688677 | 0.76 | LTB4R (0.44) | PSMB5LTB4RLTB4R2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4197557-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES | Gexval Inc. (JP) | 2023-06-21 | — | — | EP | disclosed |
| EP-3925623-A1 | MEDICINAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES | Gexval Inc. (JP) | 2021-12-22 | — | — | EP | disclosed |