Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115366 | 0.82 | PSMB5 (0.41) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL28207711 | 0.79 | LTB4R (0.39) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL2688677 | 0.76 | LTB4R (0.44) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL6099078 | 0.76 | LTB4R (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL28031588 | 0.76 | DRD2 (0.44) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL506552 | 0.76 | CYP2D6 (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL2316932 | 0.76 | LTB4R (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL2316931 | 0.76 | LTB4R (0.47) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL19574896 | 0.76 | LTB4R (0.44) | LTB4RLTB4R2PSMB5DRD2DRD3 | |
| SCHEMBL14124137 | 0.73 | LTB4R (0.41) | LTB4RLTB4R2PSMB5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047176-A | Synthetic method with chiral quaternary carbon center Dihydrobenzofuranes compound | 常州合全药业有限公司 | 2018-05-18 | — | — | CN | disclosed |