Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422719 | 0.95 | PTGDR2 (0.33) | PTGDR2FPR1HSD17B10ADAM17 | |
| SCHEMBL1278109 | 0.90 | FPR1 (0.34) | PTGDR2FPR1HSD17B10ABCC9ABCC8 | |
| SCHEMBL4422713 | 0.88 | — | — | |
| SCHEMBL1156216 | 0.88 | NAMPT (0.38) | PTGDR2FPR1HSD17B10GAATSHR | |
| SCHEMBL1156935 | 0.88 | POLB (0.39) | PTGDR2FPR1HSD17B10ALDH1A1NAMPT | |
| SCHEMBL1278508 | 0.88 | FPR1 (0.34) | PTGDR2FPR1HSD17B10ABCC9ABCC8 | |
| SCHEMBL1156473 | 0.86 | HTT (0.40) | NAMPT | |
| SCHEMBL1157389 | 0.86 | PTGDR2 (0.37) | PTGDR2FPR1HSD17B10ALDH1A1NAMPT | |
| SCHEMBL1278321 | 0.86 | NAMPT (0.36) | HSD17B10ADAM17TSHRSMN1; SMN2NAMPT | |
| SCHEMBL1278605 | 0.86 | POLB (0.34) | PTGDR2FPR1HSD17B10ABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |