Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411599 | 0.95 | PTGDR2 (0.34) | PTGDR2FPR1ADAM17HSD17B10 | |
| SCHEMBL4422713 | 0.92 | — | — | |
| SCHEMBL4792897 | 0.89 | PTGDR2 (0.33) | PTGDR2FPR1ADAM17HSD17B10 | |
| SCHEMBL1156754 | 0.87 | HSD17B10 (0.38) | FPR1ADAM17HSD17B10 | |
| SCHEMBL4791521 | 0.86 | NAMPT (0.36) | PTGDR2FPR1 | |
| SCHEMBL1278109 | 0.86 | FPR1 (0.34) | PTGDR2FPR1HSD17B10 | |
| Carbamic Acid SCHEMBL4791644 | 0.86 | HSD17B10 (0.36) | FPR1ADAM17HSD17B10 | |
| SCHEMBL4791390 | 0.85 | HSD17B10 (0.31) | PTGDR2ADAM17HSD17B10 | |
| SCHEMBL4789904 | 0.85 | MMP1 (0.36) | ADAM17 | |
| SCHEMBL1156935 | 0.84 | POLB (0.39) | PTGDR2FPR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |