Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198148 | 0.88 | NPC1 (0.54) | ALDH1A1HSD17B10APPNPC1RAB9A | |
| SCHEMBL537959 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10APPTSHRCYP3A4 | |
| SCHEMBL22198286 | 0.80 | LMNA (0.62) | ALDH1A1APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22198250 | 0.80 | NPC1 (0.71) | ALDH1A1APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9242348 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HSD17B10APPSMN1; SMN2TSHR | |
| SCHEMBL22198267 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HSD17B10APPNPC1RAB9A | |
| SCHEMBL22198264 | 0.78 | APP (0.45) | ALDH1A1APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22198276 | 0.78 | GRIN2D (0.48) | ALDH1A1APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22198268 | 0.78 | GRIN2D (0.48) | ALDH1A1APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22198265 | 0.78 | NPC1 (0.48) | ALDH1A1APPNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393810-A1 | DIHYDRAZONE COMPOUNDS HAVING HIGH AFFINITY TO A BETA PROTEIN AND TAU PROTEIN, DERIVATIVES THEREOF AND USE THEREOF | HTA Co., Ltd. (CN) | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393810-A1 | DIHYDRAZONE COMPOUNDS HAVING HIGH AFFINITY TO A BETA PROTEIN AND TAU PROTEIN, DERIVATIVES THEREOF AND USE THEREOF | MAPT, APP, PSEN1 | ALDH1A1 1343/4885HSD17B10 1254/4885APP 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.