Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272375 | 0.98 | MAPT (0.35) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9801558 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL23869469 | 0.85 | CYP3A4 (0.38) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL21540021 | 0.85 | CYP3A4 (0.38) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL25365456 | 0.84 | ALDH1A1 (0.33) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL27695746 | 0.82 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL14915004 | 0.80 | MAPT (0.36) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL14915002 | 0.80 | MAPT (0.36) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL4121949 | 0.80 | MAPT (0.36) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL14856128 | 0.80 | MAPT (0.36) | SMN1; SMN2CYP3A4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374853-A1 | Cyanate ester-based pressure sensitive adhesive | CORNERSTONE RESEARCH GROUP, INC. (US) | 2011-10-12 | — | — | EP | claimed |
| US-20100137554-A1 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RESEARCH GROUP, INC. | 2010-06-03 | — | — | US | claimed |
| US-20110294749-A1 | DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2011-12-01 | — | — | US | disclosed |
| US-20110294749-A1 | DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-1518855-B1 | DIAMINOPYRIMIDINECARBOXA MIDE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-8039572-B2 | Shape memory cyanate ester copolymers | CORNERSTONE RESEARCH GROUP, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| EP-2374831-A1 | Cyanate ester-based elastomer | CORNERSTONE RESEARCH GROUP, INC. (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374853-A1 | Cyanate ester-based pressure sensitive adhesive | CORNERSTONE RESEARCH GROUP, INC. (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-1979397-B1 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RES GROUP INC (US) | 2011-09-07 | — | — | EP | disclosed |
| US-8012959-B2 | Diaminopyrimidinecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8012959-B2 | Diaminopyrimidinecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100137554-A1 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RESEARCH GROUP, INC. | 2010-06-03 | — | — | US | disclosed |
| US-20090281072-A1 | Diaminopyrimidinecarboxamide Derivative | ASTELLAS PHARM INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281072-A1 | Diaminopyrimidinecarboxamide Derivative | ASTELLAS PHARM INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-7449456-B2 | Diaminopyrimidinecarboxamide derivative | ASTELLAS PHARMA, INC. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-7449456-B2 | Diaminopyrimidinecarboxamide derivative | ASTELLAS PHARMA, INC. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20080021188-A1 | Shape Memory Cyanate Ester Copolymers | CORNERSTONE RESEARCH GROUP, INC. | 2008-01-24 | — | — | US | disclosed |
| WO-2005108448-A1 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2005-11-17 | — | — | WO | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294749-A1 | DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE | STAT6, STAT4, STAT3 | SMN1; SMN2 4649/4885CYP3A4 2896/4885CYP2D6 476/4885 |
| US-20090281072-A1 | Diaminopyrimidinecarboxamide Derivative | STAT6, STAT4, STAT3 | SMN1; SMN2 4649/4885CYP3A4 2896/4885CYP2D6 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.