Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411752 | 0.98 | SMN1; SMN2 (0.34) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL25365456 | 0.86 | ALDH1A1 (0.33) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL27695746 | 0.84 | ALDH1A1 (0.33) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL9801558 | 0.84 | SMN1; SMN2 (0.33) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL21540021 | 0.81 | CYP3A4 (0.38) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL23869469 | 0.81 | CYP3A4 (0.38) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL20072726 | 0.81 | CYP3A4 (0.34) | MAPTALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL10233819 | 0.81 | IDO1 (0.37) | CYP2D6SLC6A3KDM4EMEN1KMT2A | |
| SCHEMBL4260116 | 0.79 | CHRM5 (0.35) | SMN1; SMN2CYP2D6SLC6A2SLC6A3MEN1 | |
| SCHEMBL3094796 | 0.79 | KMT2A (0.46) | MAPTALDH1A1SMN1; SMN2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076617-A | Electrochemical deposition of tantalum and/or copper in ionic liquids | MERCK PATENT GMBH (DE) | 2007-11-21 | — | — | CN | claimed |
| US-4483833-A | DESULFURIZATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-11-20 | — | — | US | claimed |
| EP-1717230-B1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-8268842-B2 | Fused ring 4-oxopyrimidine derivative | MSD K.K. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20110202328-A1 | System for the determination of selective absorbent molecules through predictive correlations | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110202328-A1 | System for the determination of selective absorbent molecules through predictive correlations | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-08-18 | — | — | US | disclosed |
| EP-1747210-B1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | WARNER LAMBERT CO (US) | 2010-06-30 | — | — | EP | disclosed |
| US-20090242414-A1 | ELECTRONCHEMICAL DEPOSITION OF TANTALUM AND/OR COPPER IN IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090209562-A1 | Fused ring 4-oxopyrimidine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-08-20 | — | — | US | disclosed |
| US-7521455-B2 | Fused ring 4-oxopyrimidine derivative | BANYU PHARMACEUTICAL CO. LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7456164-B2 | Useful for treatment of H3-related diseases such as neurologic disorders, or inflammatory, respiratory and allergic diseases, disorders and conditions; for example, 4-[4-(1-isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile; well absorbed from gastrointestinal tract, metabolically stable | PFIZER, INC (US) | 2008-11-25 | — | — | US | disclosed |
| EP-1717230-A1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-20050267095-A1 | 3- or 4-monosubstituted phenol and thiophenol derivatives useful as H3 ligands | ZIARCO INC. | 2005-12-01 | — | — | US | disclosed |
| WO-2005108384-A1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-17 | — | — | WO | disclosed |
| EP-1593679-A1 | 3- Or 4-monosubstituted phenol derivatives useful as H3 ligands | Warner-Lambert Company LLC (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050182045-A1 | Fused ring 4-oxopyrimidine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| WO-1993010883-A1 | LEAN ACID GAS ENRICHMENT WITH SELECTIVE HINDERED AMINES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0087207-B1 | A PROCESS FOR REMOVAL OF H2S FROM GASEOUS STREAMS WITH AMINO COMPOUNDS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4483833-A | DESULFURIZATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-11-20 | — | — | US | disclosed |
| EP-0087207-A1 | A process for removal of H2S from gaseous streams with amino compounds | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182045-A1 | Fused ring 4-oxopyrimidine derivative | HRH4, HRH2, HRH3 | MAPT 3669/4885ALDH1A1 1717/4885POLB 3042/4885 |
| US-20090209562-A1 | Fused ring 4-oxopyrimidine derivative | HRH4, HRH2, HRH3 | MAPT 3669/4885ALDH1A1 1717/4885POLB 3042/4885 |
| US-20050267095-A1 | 3- or 4-monosubstituted phenol and thiophenol derivatives useful as H3 ligands | HRH4, HRH3, TLR4 | MAPT 2226/4885ALDH1A1 832/4885POLB 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.