Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964535 | 0.76 | ALDH1A1 (0.47) | ALDH1A1CYP1A2SMN1; SMN2NPC1GAA | |
| SCHEMBL517896 | 0.76 | HTR2A (0.42) | ALOX5ALDH1A1RAB9APLD1 | |
| SCHEMBL12160564 | 0.75 | KDM4E (0.44) | ALDH1A1GRM5GAAMAPTHSD17B10 | |
| SCHEMBL22367242 | 0.74 | PARP1 (0.46) | ALDH1A1CYP1A2PARP1 | |
| SCHEMBL30684899 | 0.73 | GRM5 (0.57) | SMN1; SMN2GRM5NPC1MAPTRAB9A | |
| SCHEMBL18743043 | 0.73 | GRM5 (0.57) | SMN1; SMN2GRM5NPC1MAPTRAB9A | |
| SCHEMBL699878 | 0.72 | CYP1A2 (0.58) | ALDH1A1CYP1A2SMN1; SMN2LRRK2PARP1 | |
| SCHEMBL9348013 | 0.70 | MAPT (0.47) | ALOX5ALDH1A1CYP1A2SMN1; SMN2PARP1 | |
| SCHEMBL12059732 | 0.69 | NPC1 (0.51) | ALDH1A1SMN1; SMN2GRM5NPC1GAA | |
| SCHEMBL8304689 | 0.69 | ALDH1A1 (0.52) | ALDH1A1CYP1A2SMN1; SMN2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395249-A1 | NEW ALKOXYAMINOPYRIDINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395249-A1 | NEW ALKOXYAMINOPYRIDINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | CACNA1B, CACNA1G, CACNA1D | ALOX5 1580/4885ALDH1A1 764/4885CYP1A2 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.