Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414650 | 0.91 | HDAC1 (0.46) | MEN1KMT2ASTAT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL2415460 | 0.89 | ROCK1 (0.42) | STAT3LMNALPAR1LPAR5MAPT | |
| SCHEMBL2415567 | 0.85 | MEN1 (0.43) | MEN1KMT2ASTAT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL2412122 | 0.84 | MCL1 (0.59) | MEN1KMT2ASTAT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL2410849 | 0.83 | GABRA1 (0.49) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2414194 | 0.78 | CNR2 (0.44) | MEN1KMT2ALPAR1LPAR5MCL1 | |
| SCHEMBL2414340 | 0.76 | LPAR1 (0.55) | KMT2ASTAT3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2412850 | 0.75 | HPGD (0.53) | ALDH1A1LMNAMAPT | |
| SCHEMBL2414649 | 0.74 | STAT3 (0.58) | MEN1KMT2ASTAT3LPAR1MCL1 | |
| SCHEMBL2411428 | 0.74 | LPAR1 (0.49) | KMT2ASTAT3ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |