Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414650 | 0.89 | HDAC1 (0.46) | MEN1KMT2ATSHRLPAR1LPAR5 | |
| SCHEMBL2415565 | 0.88 | STAT3 (0.51) | MEN1KMT2ABCHEACHETSHR | |
| SCHEMBL2414588 | 0.87 | LPAR1 (0.48) | MEN1KMT2ATSHRLPAR1LPAR5 | |
| SCHEMBL2412124 | 0.85 | MEN1 (0.41) | MEN1KMT2ALPAR1LPAR5ALDH1A1 | |
| SCHEMBL2415460 | 0.85 | ROCK1 (0.42) | LPAR1LPAR5KDM4ESTAT3 | |
| SCHEMBL2414646 | 0.81 | LPAR1 (0.46) | MEN1KMT2ATSHRLPAR1LPAR5 | |
| SCHEMBL2414340 | 0.79 | LPAR1 (0.55) | KMT2ATSHRLPAR1LPAR5ALDH1A1 | |
| SCHEMBL2411428 | 0.77 | LPAR1 (0.49) | KMT2ATSHRLPAR1LPAR5ALDH1A1 | |
| SCHEMBL2412850 | 0.76 | HPGD (0.53) | TSHRALDH1A1 | |
| SCHEMBL2414586 | 0.75 | LPAR1 (0.55) | MEN1KMT2ATSHRLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-1828107-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | Sanofi-Aventis Deutschland GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063697-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |