SCHEMBL24123780 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	HTR2C	P28335	1/20	0.40

▸	GHSR	Q92847	1/20	0.40

▸	WEE1	P30291	1/20	0.39

▸	NOTUM	Q6P988	2/20	0.39

▸	HTT	P42858	1/20	0.39

▸	SYK	P43405	1/20	0.38

▸	PHGDH	O43175	1/20	0.37

▸	PDE3B	Q13370	6/20	0.37

▸	PDE3A	Q14432	6/20	0.37

▸	RBP4	P02753	2/20	0.37

▸	KCNH2	Q12809	1/20	0.36

▸	SCN5A	Q14524	1/20	0.36

▸	HTR6	P50406	1/20	0.35

▸	ASIC3	Q9UHC3	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25678510	0.83	HTR2C (0.40)	HTR2CWEE1NOTUMHTTPHGDH
SCHEMBL16541459	0.83	MAPT (0.47)	HTR2CWEE1NOTUMHTTPDE3B
SCHEMBL17708399	0.83	RBP4 (0.40)	NOTUMSYKPHGDHPDE3BPDE3A
SCHEMBL20180600	0.81	WDR5 (0.41)	NOTUMSYKPHGDHRBP4
SCHEMBL21336837	0.80	HTT (0.42)	GHSRHTTHTR6
SCHEMBL30345809	0.79	RBP4 (0.44)	HTR2CHTTRBP4
SCHEMBL30345707	0.79	RBP4 (0.44)	HTR2CHTTRBP4
SCHEMBL23744701	0.79	RBP4 (0.44)	HTR2CHTTRBP4
SCHEMBL23744698	0.79	RBP4 (0.44)	HTR2CHTTRBP4
SCHEMBL26406996	0.78	HTT (0.50)	GHSRHTTKCNH2SCN5AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021254389-A1	PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR	微境生物医药科技(上海)有限公司	2021-12-23	—	—	WO	disclosed