SCHEMBL24124140

SCHEMBL24124140

CNC(=O)[C@H]1CC12CN(C)C2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24124141 1.00 LMNA (0.30) LMNAHPGD
SCHEMBL26485065 0.82 GRM2 (0.31)
SCHEMBL26485069 0.82 GRM2 (0.31)
SCHEMBL23077133 0.80 BCHE (0.35)
SCHEMBL23077179 0.79 LMNA (0.43) LMNAHPGD
SCHEMBL19539238 0.79
SCHEMBL19566786 0.75 LMNA (0.49) LMNAHPGD
SCHEMBL13411548 0.75 LMNA (0.49) LMNAHPGD
SCHEMBL1634885 0.73 LMNA (0.44) LMNAHPGD
SCHEMBL1635905 0.73 LMNA (0.44) LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323345-A1 UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES ARCTURUS THERAPEUTICS, INC. 2023-10-12 US disclosed
WO-2021257916-A1 UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES ARCTURUS THERAPEUTICS, INC. (US) 2021-12-23 WO disclosed
WO-2021257917-A1 UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES ARCTURUS THERAPEUTICS, INC. (US) 2021-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230323345-A1 UNA OLIGOMERS FOR THE TREATMENT OF POLYGLUTAMINE DISEASES UPF1, HNRNPUL1, HNRNPUL2 LMNA 657/4885HPGD 4641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.