Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124178 | 0.81 | HDAC3 (0.54) | HDAC3HDAC1HDAC2NCOR2SLC1A2 | |
| SCHEMBL24124180 | 0.81 | NR1H4 (0.68) | KMT2ANR1H4 | |
| SCHEMBL24124921 | 0.78 | KMT2A (0.50) | HDAC3HDAC1HDAC2NCOR2KMT2A | |
| SCHEMBL24124788 | 0.76 | HDAC1 (0.54) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL24124923 | 0.74 | KMT2A (0.51) | HPSEKMT2ANR1H4KCNK3KCNK9 | |
| SCHEMBL24124948 | 0.73 | HDAC1 (0.44) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL25922050 | 0.73 | MAPT (0.65) | ACKR3KMT2A | |
| SCHEMBL24124210 | 0.72 | HDAC3 (0.46) | HDAC3HDAC1HDAC2NCOR2HPSE | |
| SCHEMBL24124913 | 0.72 | TRPV1 (0.51) | HDAC8HDAC6HDAC1HIF1ASENP1 | |
| SCHEMBL1287947 | 0.72 | HIF1A (0.83) | HDAC8HDAC6HIF1AHDAC4MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257544-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-23 | — | — | WO | disclosed |